Provided is an internal combustion engine malfunction diagnosis apparatus capable of diagnosing the deterioration of an internal combustion engine with a high accuracy and capable of diagnosing deterioration of a fluctuation factor detection section of the engine with a high accuracy in irrespective of the engine speed.According to one embodiment of the present invention, there is provided a malfunction diagnosis apparatus for an internal combustion engine comprises: a crank angle detection sensor for detecting a crank angle of the internal combustion engine; a fluctuation factor measurement means for measuring a state of a fluctuation factor of the internal combustion engine; an angular-based data sampling section for sampling data of an output signal from the fluctuation factor measurement means at a predetermined rotation angle of a crank shaft in accordance with a crank angle signal from the crank angle detection sensor; a malfunction judgement section for judging a malfunction of the internal combustion engine on the basis of data sampled by the angular-based data sampling section; a time-based data sampling section for sampling an output signal from the fluctuation factor measurement means at every lapse of a predetermined constant time; and a fluctuation factor measurement means deterioration judgement section for judging deterioration of the fluctuation factor measurement means on the basis of data sampled by the time-based data sampling section.