A spiro-oxazine compound represented by the following general formula (A) or (A') is a photochromic compound having an excellent fatigue resistance to repetition of coloration and decoloration and an abundance of hues: ##STR1## wherein the .alpha. ring is a ring selected from a 5-membered ring having one N atom, which may be connected to a benzene ring or naphthalene ring, and a 6-membered ring having one N atom, with the proviso that the N atom in the e ring is bonded to a C.sub.1-20 alkyl or another organic group, X is selected from O, S, Se and N-R.sup.1 (in which R.sup.1 is selected from H, and C.sub.1-20 alkyl and other organic groups), R.sup.2 and R.sup.3 are selected from --OH, amino, C.sub.1-20 alkoxy, halogen, and other groups, and k is an integer of 0 to 2.