发明授权
- 专利标题： Thrombin inhibitors
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申请号： US444245申请日： 1995-05-19
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公开(公告)号： US5563156A公开(公告)日： 1996-10-08
- 发明人: Bernhard Neises , Axel Ganzhorn , C eline Tarnus , Robert J. Broersma, Jr.
- 申请人： Bernhard Neises , Axel Ganzhorn , C eline Tarnus , Robert J. Broersma, Jr.
- 申请人地址： OH Cincinnati
- 专利权人： Merrell Pharmaceuticals Inc.
- 当前专利权人： Merrell Pharmaceuticals Inc.
- 当前专利权人地址： OH Cincinnati
- 优先权： EPX91400713 19910315
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; C07K5/06 ; C07K5/087 ; A61K31/445 ; A61K31/40
摘要：
This invention relates to novel polyfluorinated alkyl derivatives of certain tripeptides, to the methods for their preparation, the intermediates therefore, to their use in inhibiting thrombin and lung tryptase and in their end-use application as anti-coagulants useful in treating thrombophlebitis and coronary thrombosis and in the treatment of asthma.
公开/授权文献
- US5017949A Table assembly for pattern drawing apparatus 公开/授权日：1991-05-21
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