发明授权
US5573907A Detecting and amplifying target nucleic acids using exonucleolytic
activity
失效
使用外源核酸分解活性检测和扩增靶核酸
- 专利标题： Detecting and amplifying target nucleic acids using exonucleolytic activity
- 专利标题（中）： 使用外源核酸分解活性检测和扩增靶核酸
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申请号： US101877申请日： 1993-08-04
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公开(公告)号： US5573907A公开(公告)日： 1996-11-12
- 发明人: John J. Carrino , Uwe Spies , Laurie A. Rinehardt , Edward K. Pabich
- 申请人： John J. Carrino , Uwe Spies , Laurie A. Rinehardt , Edward K. Pabich
- 申请人地址： IL Abbott Park
- 专利权人： Abbott Laboratories
- 当前专利权人： Abbott Laboratories
- 当前专利权人地址： IL Abbott Park
- 主分类号： C07H21/00
- IPC分类号： C07H21/00 ; C12Q1/68 ; C07H21/04 ; C12P19/34
摘要：
The present invention relates to improved LCR amplification schemes using at least one downstream probe modified at its 5' end to reduce or eliminate target independent amplification. The different modified probes, and kits containing them are also presented. Also presented is a method for detecting differences in nucleic acid sequences, with reduced target independent amplification, using the modified probes.
公开/授权文献
- USD413036S Display shelf 公开/授权日：1999-08-24
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