发明授权
US5576324A Quinoline derivatives or salt thereof and remedy for cardiac diseases
containing the same
失效
喹啉衍生物或其盐和含有其的心脏疾病的治疗药物
- 专利标题： Quinoline derivatives or salt thereof and remedy for cardiac diseases containing the same
- 专利标题（中）： 喹啉衍生物或其盐和含有其的心脏疾病的治疗药物
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申请号： US325270申请日： 1994-10-27
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公开(公告)号： US5576324A公开(公告)日： 1996-11-19
- 发明人: Yoshinori Kyotani , Tadaaki Ohgiya , Tsutomu Toma , Yuji Kurihara , Takahiro Kitamura , Takashi Yamaguchi , Kazuhiro Onogi , Seiichi Sato , Hiromichi Shigyo , Tomio Ohta , Mitsuo Kawada , Yasumi Uchida
- 申请人： Yoshinori Kyotani , Tadaaki Ohgiya , Tsutomu Toma , Yuji Kurihara , Takahiro Kitamura , Takashi Yamaguchi , Kazuhiro Onogi , Seiichi Sato , Hiromichi Shigyo , Tomio Ohta , Mitsuo Kawada , Yasumi Uchida
- 申请人地址： JPX Nagoya
- 专利权人： Kowa Co., Ltd.
- 当前专利权人： Kowa Co., Ltd.
- 当前专利权人地址： JPX Nagoya
- 优先权： JPX4-112862 19920501
- 主分类号： C07D491/04
- IPC分类号： C07D491/04 ; C07D491/048 ; C07D491/056 ; A61K31/44
摘要：
A quinoline derivative represented by general formula (1), a medicinally acceptable salt thereof, and a remedy for cardiac diseases containing the same: ##STR1## [wherein ring A represents a furan, dihydrofuran or dioxolane ring, and R.sup.1 represents an aminoalkyl group].The compound (1) has a positively inotropic effect on myocardia and an antiarrhythmic effect, and can dilate blood vessels without extremely increasing the heart rate. Therefore, a remedy for cardiac diseases containing the same as the active ingredient is remarkably useful for treating cardiac insufficiency, arrhythmia, and so forth.
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