发明授权
- 专利标题: Osmium-containing redox mediator
- 专利标题(中): 含锇氧化还原介体
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申请号: US180492申请日: 1993-12-30
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公开(公告)号: US5589326A公开(公告)日: 1996-12-31
- 发明人: Zhi D. Deng , Gerald F. Sigler , Nigel A. Surridge , Christopher D. Wilsey , Robert J. McEnroe , Walter W. Jernigan , Rebecca W. Muddiman
- 申请人: Zhi D. Deng , Gerald F. Sigler , Nigel A. Surridge , Christopher D. Wilsey , Robert J. McEnroe , Walter W. Jernigan , Rebecca W. Muddiman
- 申请人地址: IN Indianapolis
- 专利权人: Boehringer Mannheim Corporation
- 当前专利权人: Boehringer Mannheim Corporation
- 当前专利权人地址: IN Indianapolis
- 主分类号: C07F15/00
- IPC分类号: C07F15/00 ; C12Q1/00 ; C12Q1/26 ; C12Q1/37
摘要:
A new group of Os(II) and Os(III) compounds useful as redox mediators in electrochemical biosensors. These compounds have 1) low oxidation potential, 2) fast reaction kinetics between the electroactive center of an enzyme and the compound, 3) slow oxidation of osmium by oxygen, and 4) excellent solubility in aqueous medium. These mediators are particularly useful as a component of a reagent used in an electrochemical biosensor, wherein the biosensor is useful for measuring analytes from a biological fluid, such as blood.
公开/授权文献
- US4794583A Disk loader 公开/授权日:1988-12-27
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