发明授权
- 专利标题: Cyclic amide derivatives for treating asthma
- 专利标题(中): 用于治疗哮喘的环状酰胺衍生物
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申请号: US353767申请日: 1994-12-12
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公开(公告)号: US5589489A公开(公告)日: 1996-12-31
- 发明人: Ashokkumar B. Shenvi , Robert T. Jacobs , Scott C. Miller , Cyrus J. Ohnmacht, Jr. , Chris A. Veale
- 申请人: Ashokkumar B. Shenvi , Robert T. Jacobs , Scott C. Miller , Cyrus J. Ohnmacht, Jr. , Chris A. Veale
- 申请人地址: GBX London
- 专利权人: Zeneca Limited
- 当前专利权人: Zeneca Limited
- 当前专利权人地址: GBX London
- 优先权: GBX9325654 19931215; GBX9423248 19941117
- 主分类号: A61K31/40
- IPC分类号: A61K31/40 ; A61P11/00 ; C07D401/06 ; C07D401/14 ; A61K31/445
摘要:
Compounds of formula I ##STR1## wherein Q.sup.1, Q.sup.2, Q.sup.3, and Q.sup.4 have any of the meanings given in the specification, their N-oxides, and their pharmaceutically acceptable salts are nonpeptide antagonists of neurokinin A and useful for the treatment of asthma, etc. Also disclosed are pharmaceutical compositions, processes for preparing the compounds of formula I and intermediates.
公开/授权文献
- US4987712A Brick cladding assembly 公开/授权日:1991-01-29
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