发明授权
- 专利标题： Phospholipase A.sub.2 inhibitor
- 专利标题（中）： 磷脂酶A2抑制剂
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申请号： US571698申请日： 1995-12-13
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公开(公告)号： US5597943A公开(公告)日： 1997-01-28
- 发明人: Mitsuaki Ohtani , Shigeru Matsutani , Tadashi Yoshida , Kazushige Tanaka , Yasuhiko Fujii , Kazuhiro Shirahase
- 申请人： Mitsuaki Ohtani , Shigeru Matsutani , Tadashi Yoshida , Kazushige Tanaka , Yasuhiko Fujii , Kazuhiro Shirahase
- 申请人地址： JPX Osaka
- 专利权人： Shionogi & Co., Ltd.
- 当前专利权人： Shionogi & Co., Ltd.
- 当前专利权人地址： JPX Osaka
- 优先权： JPX3-162847 19910703
- 主分类号： C07C69/773
- IPC分类号： C07C69/773 ; C07C69/90 ; C07C69/92 ; C07C229/36 ; C07C271/22 ; C07C317/44 ; C07C323/62 ; C07D309/38 ; C07D493/10 ; C07C69/76
摘要：
The present invention relates to the new thielocin derivatives, which exhibit phospholipase A.sub.2 inhibitory activity of the formula: ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, and R.sup.8 are independently hydrogen, lower alkyl, lower alkoxy, hydroxy, or halogen;E.sub.1 and E.sub.2 are independently hydrogen, or an ester residue;m and n are independently an integer of 0 to 4;--Y-- is a bivalent group which is selected from the group consisiting of the following radicals: ##STR2## or the salts thereof.
公开/授权文献
- US5060403A Adjustable closure device particularly for ski boots 公开/授权日：1991-10-29
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