发明授权
- 专利标题: Bisphosphonic acid derivatives as anti-arthritic agents
- 专利标题(中): 双膦酸衍生物作为抗关节炎剂
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申请号: US345508申请日: 1994-11-28
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公开(公告)号: US5602115A公开(公告)日: 1997-02-11
- 发明人: Richard A. Nugent
- 申请人: Richard A. Nugent
- 申请人地址: MI Kalamazoo
- 专利权人: The Upjohn Company
- 当前专利权人: The Upjohn Company
- 当前专利权人地址: MI Kalamazoo
- 主分类号: A61K31/66
- IPC分类号: A61K31/66 ; A61K31/665 ; A61K31/67 ; A61K31/675 ; A61P29/00 ; A61P43/00 ; C07F9/38 ; C07F9/40 ; C07F9/58 ; C07F9/60 ; C07F9/6533 ; C07F9/6539 ; C07F9/6541 ; C07F9/655 ; C07F9/6553 ; C07F9/6568 ; C07F9/6571 ; C07F9/576 ; C07F9/547
摘要:
The bisphosphonates of formula (III)R.sub.2 --X--(CW).sub.m1 --CR.sub.3 R.sub.4 --CH.sub.2 --CM[PO--(OR.sub.1).sub.2 ].sub.2 (III)bicyclic bisphosphonates (V), and cyclic bisphosphonates (VII) are useful as antiarthritic agents and do not have the side effects of anti-arthritic agents which are prostaglandin synthetase inhibitors.
公开/授权文献
- USD315548S Connecting element for use in a switch housing 公开/授权日:1991-03-19