发明授权
- 专利标题: Ellipticine derivative and process for preparing the same
- 专利标题(中): 椭圆衍生物及其制备方法
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申请号: US449273申请日: 1995-05-24
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公开(公告)号: US5605904A公开(公告)日: 1997-02-25
- 发明人: Kenji Tsujihara , Naoyuki Harada , Kunihiko Ozaki , Motoaki Ohashi , Koji Oda
- 申请人: Kenji Tsujihara , Naoyuki Harada , Kunihiko Ozaki , Motoaki Ohashi , Koji Oda
- 申请人地址: JPX Osaka
- 专利权人: Tanabe Seiyaku Co., Ltd.
- 当前专利权人: Tanabe Seiyaku Co., Ltd.
- 当前专利权人地址: JPX Osaka
- 优先权: JPX5-013441 19930129
- 主分类号: C07D471/04
- IPC分类号: C07D471/04 ; A61K31/435
摘要:
An ellipticine derivative of the formula [I]: ##STR1## wherein R is a substituted lower alkyl group, a substituted or unsubstituted lower alkoxy group or a heteromonocyclic group, or a pharmaceutically acceptable salt thereof, which show excellent antitumor activity, less side effects, less toxicity and/or high solubility in water and are useful as antitumor agent, and a process for preparing the same.