发明授权
- 专利标题： Treatment of obsessive-compulsive disorders with 5-HT.sub.2 antagonists
- 专利标题（中）： 用5-HT2拮抗剂治疗强迫症
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申请号： US209084申请日： 1994-03-09
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公开(公告)号： US5618824A公开(公告)日： 1997-04-08
- 发明人: Christopher J. Schmidt , John H. Kehne , Robert A. Padich
- 申请人： Christopher J. Schmidt , John H. Kehne , Robert A. Padich
- 申请人地址： OH Cincinnati
- 专利权人： Merrell Pharmaceuticals Inc.
- 当前专利权人： Merrell Pharmaceuticals Inc.
- 当前专利权人地址： OH Cincinnati
- 主分类号： C07D211/22
- IPC分类号： C07D211/22 ; A61K31/445 ; A61K31/451 ; A61K45/00 ; A61P43/00
摘要：
The present invention is directed to 5-HT.sub.2 antagonists and their use as agents in the treatment of obsessive-compulsive disorders (OCD). The invention is particularly directed to the compound (+)-.alpha.-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol which is a member of a class of 5-HT.sub.2 antagonists known as N-aralkyl piperidinemethanol derivatives which are potent and selective inhibitors of the binding of serotonin at the 5-HT.sub.2 receptor site.
公开/授权文献
- US4382618A Hydraulic coupling device 公开/授权日：1983-05-10
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