发明授权
- 专利标题： Dihydropyridine npy antagonists: piperazine derivatives
- 专利标题（中）： 二氢吡啶npy拮抗剂：哌嗪衍生物
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申请号： US482355申请日： 1995-06-07
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公开(公告)号： US5635503A公开(公告)日： 1997-06-03
- 发明人: Graham S. Poindexter , Marc Bruce , Graham Johnson , Michael Kozlowski , Karen LeBoulluec , Ivo Monkovic , Ramakrishna Seethala , Charles P. Sloan
- 申请人： Graham S. Poindexter , Marc Bruce , Graham Johnson , Michael Kozlowski , Karen LeBoulluec , Ivo Monkovic , Ramakrishna Seethala , Charles P. Sloan
- 申请人地址： NJ Princeton
- 专利权人： Bristol-Myers Squibb Company
- 当前专利权人： Bristol-Myers Squibb Company
- 当前专利权人地址： NJ Princeton
- 主分类号： A61K31/4427
- IPC分类号： A61K31/4427 ; A61K31/445 ; A61K31/451 ; A61K31/455 ; A61K31/495 ; A61K31/55 ; A61P3/04 ; A61P9/12 ; A61P25/20 ; A61P25/24 ; A61P25/26 ; A61P43/00 ; C07D211/90 ; C07D401/12 ; C07D413/04 ; C07D413/14 ; A61K31/435
摘要：
A series of non-peptidergic antagonists of NPY have been synthesized and are comprised of piperazine and homopiperazine derivatives of 4-phenyl-1,4-dihydropyridines of Formula (I). ##STR1## As antagonists of NPY-induced feeding behavior, these compounds are expected to act as effective anorexiant agents in promoting weight loss and treating eating disorders.
公开/授权文献
- USD329613S Wristwatch 公开/授权日：1992-09-22
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