Invention Grant
- Patent Title: Peptides that bind IL-2 receptors
- Patent Title (中): 结合IL-2受体的肽
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Application No.: US250789Application Date: 1994-05-27
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Publication No.: US5635597APublication Date: 1997-06-03
- Inventor: Ronald W. Barrett , Tania Chernov-Rogan , Ann M. Davis
- Applicant: Ronald W. Barrett , Tania Chernov-Rogan , Ann M. Davis
- Applicant Address: ANX Curacao
- Assignee: Affymax Technologies, N.V.
- Current Assignee: Affymax Technologies, N.V.
- Current Assignee Address: ANX Curacao
- Main IPC: A61K38/00
- IPC: A61K38/00 ; C07K7/08 ; C07K14/715
Abstract:
Peptides that bind to the Interleukin-2 (IL-2) receptor subunits IL-2R.alpha., IL-2R.beta. and IL-2R.gamma., and inhibit the binding of IL-2 to these important receptors, are described. The invention also includes methods for treating diseases related to the activation of these receptors, as well as the receptors for IL-4, -7 and -13. In addition, the present invention also includes methods for assaying for the presence of these receptors on cell surfaces.
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