发明授权
- 专利标题: Peptides that bind IL-2 receptors
- 专利标题(中): 结合IL-2受体的肽
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申请号: US250789申请日: 1994-05-27
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公开(公告)号: US5635597A公开(公告)日: 1997-06-03
- 发明人: Ronald W. Barrett , Tania Chernov-Rogan , Ann M. Davis
- 申请人: Ronald W. Barrett , Tania Chernov-Rogan , Ann M. Davis
- 申请人地址: ANX Curacao
- 专利权人: Affymax Technologies, N.V.
- 当前专利权人: Affymax Technologies, N.V.
- 当前专利权人地址: ANX Curacao
- 主分类号: A61K38/00
- IPC分类号: A61K38/00 ; C07K7/08 ; C07K14/715
摘要:
Peptides that bind to the Interleukin-2 (IL-2) receptor subunits IL-2R.alpha., IL-2R.beta. and IL-2R.gamma., and inhibit the binding of IL-2 to these important receptors, are described. The invention also includes methods for treating diseases related to the activation of these receptors, as well as the receptors for IL-4, -7 and -13. In addition, the present invention also includes methods for assaying for the presence of these receptors on cell surfaces.
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