发明授权
- 专利标题： Methods for the preparation of nucleic acids for in vivo delivery
- 专利标题（中）： 用于制备用于体内递送的核酸的方法
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申请号： US483295申请日： 1995-06-07
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公开(公告)号： US5639473A公开(公告)日： 1997-06-17
- 发明人: Mark W. Grinstaff , Patrick Soon-Shiong , Michael Wong , Paul A. Sandford , Kenneth S. Suslick , Neil P. Desai
- 申请人： Mark W. Grinstaff , Patrick Soon-Shiong , Michael Wong , Paul A. Sandford , Kenneth S. Suslick , Neil P. Desai
- 申请人地址： CA Santa Monica
- 专利权人： Vivorx Pharmaceuticals, Inc.
- 当前专利权人： Vivorx Pharmaceuticals, Inc.
- 当前专利权人地址： CA Santa Monica
- 主分类号： A23L33/00
- IPC分类号： A23L33/00 ; A61K9/00 ; A61K9/50 ; A61K9/51 ; A61K47/30 ; A61K47/48 ; A61K49/00 ; A61K49/04 ; A61K49/18 ; A61K49/22 ; A61K51/00 ; A61K9/127
摘要：
In accordance with the present invention, there are provided compositions useful for the in vivo delivery of a biologic, wherein the biologic is associated with a polymeric shell formulated from a biocompatible material. The biologic can be associated with the polymeric shell itself, and/or the biologic, optionally suspended/dispersed in a biocompatible dispersing agent, can be encased by the polymeric shell. In another aspect, the biologic associated with polymeric shell is administered to a subject, optionally dispersed in a suitable biocompatible liquid.
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