公开(公告)号：US12233099B2

公开(公告)日：2025-02-25

申请号：US17059122

申请日：2019-05-24

Applicant: GREEN CROSS WELLBEING CORPORATION

Inventor： Sun Kyu Park ,  Jeom Yong Kim ,  Young Hyo Yoo ,  Min Jung Jang ,  Chang Taek Oh ,  Min Ju Lim ,  Gwan Su Yi ,  Yi Li ,  Yoon Hyeok Lee ,  Jae Cheal Yoo

IPC: A61K36/00 ,  A23L33/00 ,  A23L33/105 ,  A61K9/00 ,  A61K31/704 ,  A61K36/258 ,  A61P21/00

Abstract: The present invention relates to a composition for promoting myogenesis, containing, as an active ingredient, a processed ginseng extract in which a trace amount of a ginsenoside ingredient is increased. It has been ascertained that the processed ginseng extract promotes the differentiation of myoblasts into muscle and inhibits muscle atrophy caused by myostatin, which is a myogenesis inhibitory factor, and thus it is expected that a composition for preventing or treating muscle disorder-related diseases, having excellent effects, can be developed.

公开(公告)号：US12233039B2

公开(公告)日：2025-02-25

申请号：US17751704

申请日：2022-05-24

Applicant: N.V. Nutricia

Inventor： Patrick Joseph Gerardus Hendrikus Kamphuis ,  Martine Groenendijk ,  Anke Bongers

IPC: A61K31/202 ,  A23L33/00 ,  A23L33/10 ,  A23L33/12 ,  A23L33/15 ,  A23L33/16 ,  A61K31/14 ,  A61K31/557 ,  A61K31/7072 ,  A61K45/06 ,  A61P25/28

Abstract: The invention thus pertains to the use of a composition comprising: (a) uridine or uridine phosphate; and (b) docosahexaenoic acid and/or eicosapentaenoic acid, for improving memory and/or the treatment or prevention of impaired memory function, in a subject with a mini-mental state examination of 24-26, wherein said composition is enterally administered to the subject. In the MMSE test, any score of 27 or higher (out of 30) is effectively normal. In the patients with dementia, 20-26 indicates mild dementia, 10-19 moderate dementia, and below 10 severe dementia. It was the present inventors' belief that within the group of 20-26, the memory impairment in the sub-group of 24-26 may even be reversible, as the pathological pathways have just started to develop. In this group of subjects the pathological pathways have just started to develop. Clinical studies show excellent results for this subgroup.

公开(公告)号：US20250057904A1

公开(公告)日：2025-02-20

申请号：US18936180

申请日：2024-11-04

Applicant: INDUSTRIAL COOPERATION FOUNDATION CHONBUK NATIONAL UNIVERSITY

Inventor： JUNG HYUN KIM

IPC: A61K36/185 ,  A23L33/00 ,  A23L33/105 ,  A61P27/02

Abstract: A method for treating macular degeneration includes administering a composition comprising an effective amount of Aucuba japonica extract to a subject in need thereof. The composition may prevent or treating macular degeneration. The macular degeneration may be age-related macular degeneration. The Aucuba japonica extract may be extracted from a 5 leaf, a stem or a mixture thereof of Aucuba japonica.

公开(公告)号：US12213506B2

公开(公告)日：2025-02-04

申请号：US17987747

申请日：2022-11-15

Applicant: DailyColors Health Inc.

Inventor： Hartley Pond

IPC: A23L33/105 ,  A23L33/00 ,  A23L33/135 ,  A23L33/15

Abstract: Contemplated compositions and methods are based on a combination of polyphenols commonly found in the Mediterranean diet that, when combined, reduce pro-inflammatory signaling and expression of senescence-associated genes and support mitochondrial biogenesis and cellular energy metabolism. Notably, the observed pleiotropic effects did not only span across multiple signaling pathways, but also exhibited synergistic activity with respect to a number of markers associated with reduction of age-related decline in energy, immunity, and increase or persistence of chronic subacute inflammation. Viewed from a different perspective, contemplated compositions represent a symphony of biochemically diverse molecules that form the foundation for numerous benefits typically observed with the Mediterranean diet.

公开(公告)号：US20250032523A1

公开(公告)日：2025-01-30

申请号：US18769471

申请日：2024-07-11

Applicant: Zhejiang Gongshang University

Inventor： Linglin FU ,  Chong WANG ,  Li WANG ,  Shunyu WANG ,  Jinru ZHOU

IPC: A61K31/702 ,  A23L33/00 ,  A61K9/08 ,  A61P37/08 ,  G01N33/50

Abstract: An active human milk oligosaccharide (HMO) preparation with an allergy-alleviating function is provided. The active HMO preparation includes one or more of lacto-N-fucopentaose I (LNFP-I) and 2′-fucosyllactose (2′-FL). A part of these two HMOs ingested by a human body can enter a circulatory system to regulate the immune cell populations and the cytokine secretion, so as to directly affect an immune system of the human body and well alleviate the allergies in some infants and young children. In addition, for infants and young children who have a human milk without 2′-FL and LNFP-I, the active HMO preparation can supplement the nutrients of the human milk.

公开(公告)号：US20250031737A1

公开(公告)日：2025-01-30

申请号：US18913589

申请日：2024-10-11

Applicant: Alcresta Therapeutics, Inc.

Inventor： Eric FIRST ,  David BROWN ,  Albert Archie STONE

IPC: A23L29/00 ,  A23L33/00 ,  A23L33/12 ,  A61J3/00 ,  A61J15/00 ,  A61K9/00 ,  A61K38/46 ,  A61K38/47 ,  A61K38/48 ,  A61M5/14 ,  A61M5/142 ,  A61M5/168 ,  C12N9/20 ,  C12N9/26 ,  C12N9/50

Abstract: Exemplary embodiments of the disclosure may be drawn to a device having an inlet and a chamber. Immobilized lipase, immobilized protease, and immobilized amylase may be contained within the chamber. The device may also include an outlet, wherein a flow path extends from the inlet, through the chamber, and to the outlet.

公开(公告)号：US12186331B2

公开(公告)日：2025-01-07

申请号：US17983992

申请日：2022-11-09

Applicant: SOCIETE DES PRODUITS NESTLE S.A.

Inventor： Clara Lucia Garcia-Rodenas ,  Jose Manuel Ramos Nieves ,  Myriam Sandrine Steinmann

IPC: A61K31/702 ,  A23L33/00 ,  A23L33/125 ,  A61K45/06

Abstract: This invention relates to compositions for use in the promotion of the development and/or of the growth of the surface area of the small intestine and in the associated improvement of the digestive capacity in an infant or in a young child.

公开(公告)号：US12185747B2

公开(公告)日：2025-01-07

申请号：US16863418

申请日：2020-04-30

Applicant: UNIVERSITY OF SOUTHERN CALIFORNIA

Inventor： Valter D. Longo ,  Min Wei ,  Priya Rangan

IPC: A23L33/20 ,  A23L33/00 ,  A61K9/00 ,  A61K47/26 ,  A61K47/42 ,  A61K47/44

Abstract: A method of treating Alzheimer's associated pathology includes a step of identifying subject having a pathology that is associated with Alzheimer's disease. A fasting mimicking diet (FMD) is then administered to the subject for a first time period. Methods for treating amyloid plaque formation and/or elevated levels of tau protein as well as neuroinflammation are also provided.

公开(公告)号：US12185744B2

公开(公告)日：2025-01-07

申请号：US18326267

申请日：2023-05-31

Applicant: Baylor College of Medicine

Inventor： Antone Robert Opekun, Jr.

IPC: A23L29/00 ,  A23L33/00 ,  A61K38/47

Abstract: Embodiments of the disclosure include particular amyloglucosidase (AMG) compositions formulated as a nutriceutical or medicinal food, for example. The AMG compositions are formulated at a specific dosage and/or are lacking in one or more toxins or have substantially reduced levels of toxin, such as deoxynivalenol (vomit toxin). The AMG compositions are provided to individuals in need thereof, such as an individual with or at risk for congenital sucrase isomaltase syndrome, functional bowel disorders, small bowel bacterial overgrowth, protein-calorie malnutrition (marasmus), radiochemotherapy-induced mucositis and/or short-gut syndrome.

公开(公告)号：US12180463B2

公开(公告)日：2024-12-31

申请号：US17763542

申请日：2020-09-24

Applicant: PRECISIONBIOTICS GROUP LIMITED

Inventor： Jens Walter

IPC: C12N1/20 ,  A23L33/00 ,  A23L33/105 ,  A23L33/125 ,  A23L33/135 ,  A61K35/747 ,  C12R1/225

Abstract: Lactobacillus reuteri strain having NCIMB accession number 42835 is from a novel phylogenetic clade and has unique immune-stimulatory properties and enhanced ecological performance in the human gut. A substrate for the strain, such as raffinose, may be administered at the same time as or separately from the strain.