发明授权
US5643927A 4-p-fluorobenzoyl-1-piperidinyl-propoxy-chromen-4-one derivatives, their
preparation and their use in the treatment of psychosis and
schizophrenia
失效
4-对氟苯甲酰-1-哌啶基 - 丙氧基 - 色烯-4-酮衍生物,其制备及其在治疗精神病和精神分裂症中的应用
- 专利标题: 4-p-fluorobenzoyl-1-piperidinyl-propoxy-chromen-4-one derivatives, their preparation and their use in the treatment of psychosis and schizophrenia
- 专利标题(中): 4-对氟苯甲酰-1-哌啶基 - 丙氧基 - 色烯-4-酮衍生物,其制备及其在治疗精神病和精神分裂症中的应用
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申请号: US532791申请日: 1995-12-12
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公开(公告)号: US5643927A公开(公告)日: 1997-07-01
- 发明人: Rafael Foguet , Jordi Bolos , Aurelio Sacristan , Jose A. Ortiz
- 申请人: Rafael Foguet , Jordi Bolos , Aurelio Sacristan , Jose A. Ortiz
- 申请人地址: ESX Barcelona
- 专利权人: Ferrer Internacional, S.A.
- 当前专利权人: Ferrer Internacional, S.A.
- 当前专利权人地址: ESX Barcelona
- 优先权: ESX9400581 19940318; ESX9401437 19940701; ESX9500163 19950130
- 主分类号: A61K31/443
- IPC分类号: A61K31/443 ; A61K31/445 ; A61K31/453 ; A61P25/18 ; C07D405/12
摘要:
The present invention relates to new chromene compounds of the general formula (I): ##STR1## wherein R.sub.1 and R.sub.2 are hydrogen, alkyl having from 1 to 4 carbon atoms, halogen, trifluoromethyl, optionally substituted phenyl, or hydroxymethyl, as well as their pharmaceutically acceptable addition salts.These compounds are useful in the treatment of psychosis and schizophrenia.
公开/授权文献
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