发明授权
- 专利标题: Process for preparing (R)-3-amino-5-methoxychroman
- 专利标题(中): 制备(R)-3-氨基-5-甲氧基苯并二氢吡喃的方法
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申请号: US451983申请日: 1995-05-26
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公开(公告)号: US5650524A公开(公告)日: 1997-07-22
- 发明人: Lars-Gunnar Larsson
- 申请人: Lars-Gunnar Larsson
- 申请人地址: SEX Sodertalje
- 专利权人: Astra Aktiebolag
- 当前专利权人: Astra Aktiebolag
- 当前专利权人地址: SEX Sodertalje
- 优先权: SEX8904361 19891222; SEX9102905 19911008; SEX9202000 19920629
- 主分类号: C07D311/58
- IPC分类号: C07D311/58 ; A61K31/35 ; A61K31/352 ; A61K31/353 ; A61P9/12 ; A61P25/04 ; A61P25/06 ; A61P25/24 ; A61P25/26 ; A61P25/28 ; C07D335/06 ; C07D405/04 ; C07D405/12 ; C07D407/04 ; C07D409/04 ; C07D409/06 ; C07D409/12 ; C07D413/04 ; C07D413/06 ; C07D417/12
摘要:
A process for preparing (R)-3-amino-5-methoxychroman is provided. The process comprises the steps of (i) dissolving racemic 3-amino-5-methoxychroman and L(+)tartaric acid in water to form the tartrate salt; (ii) heating the solution until a clear solution is obtained; and (iii) crystallizing the tartrate salt by allowing the solution to cool to room temperature.
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