发明授权
- 专利标题： Bicyclic amine derivatives
- 专利标题（中）： 双环胺衍生物
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申请号： US172233申请日： 1993-12-23
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公开(公告)号： US5654318A公开(公告)日： 1997-08-05
- 发明人: Makoto Takemura , Youichi Kimura , Norikazu Matsuhashi
- 申请人： Makoto Takemura , Youichi Kimura , Norikazu Matsuhashi
- 申请人地址： JPX Tokyo
- 专利权人： Daiichi Pharmaceutical Co., Ltd.
- 当前专利权人： Daiichi Pharmaceutical Co., Ltd.
- 当前专利权人地址： JPX Tokyo
- 优先权： JPX4-346030 19921225
- 主分类号： A61K31/435
- IPC分类号： A61K31/435 ; A61K31/47 ; A61K31/4709 ; A61K31/5383 ; A61P31/00 ; A61P31/04 ; C07D215/233 ; C07D401/04 ; C07D471/04 ; C07D487/04 ; C07D491/04 ; C07D495/04 ; C07D497/04 ; C07D498/04 ; C07D513/04 ; C07D519/00 ; C07D209/02 ; C07D215/12 ; C07D215/56
摘要：
A compound represented by formula (I) or a salt thereof: ##STR1## wherein X.sup.1 and X.sup.2 each represent a halogen atom;R.sup.1 represents a hydrogen atom or a substituent;R.sup.2 represents a substituted or unsubstituted bicyclic heterocyclic substituent of the following formula; ##STR2## wherein R.sup.3, R.sup.4, Y, Z, m, n, p, q and r are as defined herein;A represents a nitrogen atom or a substituted carbon atom; andR represents a hydrogen atom or a substituent. The compound exhibits potent antimicrobial activity and also high safety due to reduced lipophilicity.
公开/授权文献
- US4863423A Catheter and cannula assembly 公开/授权日：1989-09-05
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