发明授权
- 专利标题： Methods and compositions for stimulating neurite growth
- 专利标题（中）： 刺激神经突生长的方法和组合物
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申请号： US486004申请日： 1995-06-08
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公开(公告)号： US5654332A公开(公告)日： 1997-08-05
- 发明人: David M. Armistead
- 申请人： David M. Armistead
- 申请人地址： MA Cambridge
- 专利权人： Vertex Pharmaceuticals Incorporated
- 当前专利权人： Vertex Pharmaceuticals Incorporated
- 当前专利权人地址： MA Cambridge
- 主分类号： A61K31/197
- IPC分类号： A61K31/197 ; A61K31/34 ; A61K31/40 ; A61K31/401 ; A61K31/4025 ; A61K31/4427 ; A61K31/4439 ; A61K31/444 ; A61K31/445 ; A61K31/4525 ; A61K31/4535 ; A61K31/454 ; A61K31/4545 ; A61K31/496 ; A61K31/506 ; A61K31/52 ; A61K31/5377 ; A61K38/18 ; A61P25/18 ; A61K31/235 ; A61K31/22 ; A61K31/225 ; A61K31/24 ; A61K31/36 ; A61K31/38 ; A61K31/44
摘要：
The present invention relates to methods and pharmaceutical compositions for stimulating the growth of neurites in nerve cells. The compositions comprise a neurotrophic amount of a compound which binds to the FK-506 binding protein (FKBP) and a neurotrophic factor, such as nerve growth factor NGF. The methods comprise treating nerve cells with the above-described compositions or compositions comprising the FKBP binding compound without a neurotrophic factor. The methods of this invention can be used to promote repair of neuronal damage caused by disease or physical trauma.
公开/授权文献
- US6037370A Methods and compositions for stimulating neurite growth 公开/授权日：2000-03-14
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