A motor-driven cart includes a manned/unmanned operation change-over switch, first and second electric motors for driving the cart, a handle lever provided to a main body of the cart to be swung to a predetermined angle with respect to a left, right, forward or backward direction, and a device for generating electric signal for steering and for speed control in response to a swing operation of the handle lever. When an operator changes the manned/unmanned operation change-over switch to its manned operation side and the handle lever is placed in its neutral zone, the motors are put in their stopped state. When the operator manipulates the handle lever in the left, right, forward or backward direction to a position outside the neutral zone, the forward or reverse rotational speeds of the first and second motors are increased in proportion to the extent of the swing operation to turn the cart to the left or right direction or to perform the forward or backward speed control. When the operator's hand is released from the handle lever, this causes the lever to be automatically returned to the neutral zone nearly in the middle of pivotal center by a restoring force of four spring members.