发明授权
- 专利标题： Bi-directional oligonucleotides that bind thrombin
- 专利标题（中）： 结合凝血酶的双向寡核苷酸
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申请号： US539516申请日： 1995-12-11
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公开(公告)号： US5658738A公开(公告)日： 1997-08-19
- 发明人: James G. Nadeau , Mary Lee Ciolkowski , Erwin A. Vogler
- 申请人： James G. Nadeau , Mary Lee Ciolkowski , Erwin A. Vogler
- 申请人地址： NJ Franklin Lakes
- 专利权人： Becton Dickinson and Company
- 当前专利权人： Becton Dickinson and Company
- 当前专利权人地址： NJ Franklin Lakes
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; C07H21/00 ; C12N15/113 ; C12Q1/68 ; A01N43/72 ; C07H21/04
摘要：
The present invention relates to bi-directional nucleic acid ligand compounds wherein at least two oligonucleotides of opposite sequence polarity are linked to a connecting compound at their same respective terminii; either the 5' terminii or the 3' terminii. These compounds are useful for binding protein or small molecule targets and thus may be used as diagnostic or therapeutic agents.
公开/授权文献
- USD327429S Soap and powder dispenser 公开/授权日：1992-06-30
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