发明授权
- 专利标题： Imidazoquinazoline derivatives
- 专利标题（中）： 咪唑喹唑啉衍生物
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申请号： US424274申请日： 1995-04-26
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公开(公告)号： US5661147A公开(公告)日： 1997-08-26
- 发明人: Daisuke Machii , Kenji Matsuno , Iwao Kinoshita , Yuji Nomoto , Haruki Takai , Tetsuji Ohno , Ken Nagashima , Tomoko Ishikawa , Koji Yamada , Michio Ichimura , Hiroshi Kase
- 申请人： Daisuke Machii , Kenji Matsuno , Iwao Kinoshita , Yuji Nomoto , Haruki Takai , Tetsuji Ohno , Ken Nagashima , Tomoko Ishikawa , Koji Yamada , Michio Ichimura , Hiroshi Kase
- 申请人地址： JPX Tokyo
- 专利权人： Kyowa Hakko Kogyo Co., Ltd.
- 当前专利权人： Kyowa Hakko Kogyo Co., Ltd.
- 当前专利权人地址： JPX Tokyo
- 优先权： JPX5-219595 19930903
- 主分类号： C07D487/04
- IPC分类号： C07D487/04 ; C07D417/04 ; A61K31/505 ; C07D243/08 ; C07D413/04
摘要：
The present invention relates to imidazoquinazoline derivatives represented by the general formula (I): ##STR1## or pharmacologically acceptable salts thereof. The compounds of the present invention have strong and selective cGMP-specific PDE inhibitory activity and are useful for treating or ameliorating cardiovascular diseases such as thrombosis, angina pectoris, hypertension, arterial sclerosis and the like, as well as asthma and the like.
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