- 专利标题: Capsular polysaccharide immunomodulator
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申请号: US301271申请日: 1994-09-02
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公开(公告)号: US5679654A公开(公告)日: 1997-10-21
- 发明人: Arthur O. Tzianabos , Andrew B. Onderdonk , Dennis L. Kasper
- 申请人: Arthur O. Tzianabos , Andrew B. Onderdonk , Dennis L. Kasper
- 申请人地址: MA Boston
- 专利权人: Brigham & Women's Hospital, Inc.
- 当前专利权人: Brigham & Women's Hospital, Inc.
- 当前专利权人地址: MA Boston
- 主分类号: A61K39/114
- IPC分类号: A61K39/114 ; A61K31/715 ; A61K31/725 ; A61K31/73 ; A61K39/02
摘要:
Methods and products for protecting against abscess formation associated with surgery, trauma or diseases that predispose the host to abscess formation are provided. Methods for forming immunomodulators and pharmaceutical compositions relating thereto also are provided. The products useful in the invention are polysaccharides including a repeat unit having a positively charged free amino group and a negatively charged group. The preferred polysaccharide is B. fragilis capsular polysaccharide A.