发明授权
- 专利标题： Class of phosphocholine derivatives having antifungal activity
- 专利标题（中）： 具有抗真菌活性的磷酸胆碱衍生物类
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申请号： US411709申请日： 1995-04-05
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公开(公告)号： US5681829A公开(公告)日： 1997-10-28
- 发明人: Michael Tempesta , Shivanand D. Jolad , Steven King , Guohua Mao , Reimar C. Bruening , John E. Kuo , Thien V. Troung , Donald E. Bierer , Jeffrey M. Dener
- 申请人： Michael Tempesta , Shivanand D. Jolad , Steven King , Guohua Mao , Reimar C. Bruening , John E. Kuo , Thien V. Troung , Donald E. Bierer , Jeffrey M. Dener
- 申请人地址： CA South San Francisco
- 专利权人： Shaman Pharmaceuticals, Inc.
- 当前专利权人： Shaman Pharmaceuticals, Inc.
- 当前专利权人地址： CA South San Francisco
- 主分类号： A01N57/14
- IPC分类号： A01N57/14 ; A01N57/16 ; A61K31/66 ; A61K31/70 ; A61K31/7028 ; A61K36/18 ; A61K47/24 ; A61P31/04 ; A61P31/10 ; C07F9/09 ; C07F9/10 ; C07F9/655 ; C07G3/00 ; C07H15/04 ; C07H15/18 ; C07F9/02
摘要：
Certain phosphocholine derivatives having substantial antifungal therapeutic activity are disclosed. The phosphocholine derivatives may be chemically synthesized, enzymatically prepared or extracted from the plant Irlbachia alata. The phosphocholine derivatives are useful in treating fungal infections including those which are dermatophytic, systemic, ophthalmic and vaginal.
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