发明授权
- 专利标题： Determination of oligonucleotides for therapeutics, diagnostics and research reagents
- 专利标题（中）： 测定治疗，诊断和研究试剂的寡核苷酸
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申请号： US330000申请日： 1994-10-27
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公开(公告)号： US5686242A公开(公告)日： 1997-11-11
- 发明人: Thomas W. Bruice , Walter F. Lima
- 申请人： Thomas W. Bruice , Walter F. Lima
- 申请人地址： CA Carlsbad
- 专利权人： ISIS Pharmaceuticals, Inc.
- 当前专利权人： ISIS Pharmaceuticals, Inc.
- 当前专利权人地址： CA Carlsbad
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; C07H21/00 ; G01N33/53
摘要：
Oligonucleotides which selectively bind to target biomolecules are determined by in vitro assay of a pool of random oligonucleotides for activity against said biomolecules, followed by recovery and characterization of selected oligonucleotides. Oligonucleotides so determined may be utilized for therapeutic, diagnostic and research reagent purposes.
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