发明授权
US5690952A Implantable system for delivery of fluid-sensitive agents to animals
失效
用于向动物输送流体敏感剂的植入系统
- 专利标题: Implantable system for delivery of fluid-sensitive agents to animals
- 专利标题(中): 用于向动物输送流体敏感剂的植入系统
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申请号: US485870申请日: 1995-06-07
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公开(公告)号: US5690952A公开(公告)日: 1997-11-25
- 发明人: Judy A. Magruder , James B. Eckenhoff, deceased , Richard Cortese , Jeremy C. Wright , John R. Peery , James B. Pike , Urano A. Robinson , Jonathan P. Smith , Lyle E. Ziemann
- 申请人: Judy A. Magruder , James B. Eckenhoff, deceased , Richard Cortese , Jeremy C. Wright , John R. Peery , James B. Pike , Urano A. Robinson , Jonathan P. Smith , Lyle E. Ziemann
- 申请人地址: CA Mountain View
- 专利权人: Magruder et al.; Judy A.
- 当前专利权人: Magruder et al.; Judy A.
- 当前专利权人地址: CA Mountain View
- 主分类号: A61K9/00
- IPC分类号: A61K9/00 ; A61K9/52 ; A61F2/02 ; A61K9/22
摘要:
A delivery system (10) is disclosed for delivering a fluid-sensitive beneficial agent (7) such as a somatotropin, or an analogue or derivative thereof, to an animal such as a bovine. The delivery system comprises a wall that surrounds an internal compartment, said wall comprising a first wall section that limits the passage of fluid into the system and a second wall section that permits the passage of fluid into the system. An exit passageway is provided for delivering the beneficial agent an interior compartment (18) to the animal. The exit passageway is sealed with a wax seal (30) which is expelled through the passageway (13) as the internal pressure within the device (10) reaches a predetermined "bursting" pressure. The passageway (13) is preferably sized to compensate for slight variations in the efflux of the beneficial agent and to maintaining a sufficient volumetric outflow rate of beneficial agent in order to minimize influx of biological fluids from the external environment back into the device once the seal (30) is expelled.
公开/授权文献
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