发明授权
- 专利标题： Acylated insulin analogs
- 专利标题（中）： 酰化胰岛素类似物
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申请号： US342931申请日： 1994-11-17
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公开(公告)号： US5693609A公开(公告)日： 1997-12-02
- 发明人: Jeffrey C. Baker , Jose M. Hanquier
- 申请人： Jeffrey C. Baker , Jose M. Hanquier
- 申请人地址： IN Indianapolis
- 专利权人： Eli Lilly and Company
- 当前专利权人： Eli Lilly and Company
- 当前专利权人地址： IN Indianapolis
- 主分类号： C12N15/09
- IPC分类号： C12N15/09 ; A61K38/00 ; A61K38/28 ; A61P3/08 ; A61P5/38 ; C07K14/62 ; G01N33/68
摘要：
The present invention relates to the field of diabetes. More particularly, the invention relates to a monomeric insulin analog wherein the A chain is the naturally occurring sequence of the human insulin A chain and the B chain is modified at either position B28 and B29 or both. The analog is mono-acylated at the N-terminal of the A chain or B chain or at the lysine. The acylated insulin analogs have an extended duration of action.
公开/授权文献
- US5003268A Optical signal sampling apparatus 公开/授权日：1991-03-26
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