发明授权
US5696276A Process for preparing 5,8-dihydroxynaphthoquinone derivatives, novel
5,8-dihydroxynaphthoquinone derivatives and their use as anticancer
agent
失效
制备5,8-二羟基萘醌衍生物的方法，新的5,8-二羟基萘醌衍生物及其作为抗癌剂的用途
- 专利标题： Process for preparing 5,8-dihydroxynaphthoquinone derivatives, novel 5,8-dihydroxynaphthoquinone derivatives and their use as anticancer agent
- 专利标题（中）： 制备5,8-二羟基萘醌衍生物的方法，新的5,8-二羟基萘醌衍生物及其作为抗癌剂的用途
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申请号： US403716申请日： 1995-03-14
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公开(公告)号： US5696276A公开(公告)日： 1997-12-09
- 发明人: Byung Zun Ahn , Kyong Up Baik
- 申请人： Byung Zun Ahn , Kyong Up Baik
- 申请人地址： KRX Chungnam
- 专利权人： Kuhnil Pharmaceutical Co., Ltd.
- 当前专利权人： Kuhnil Pharmaceutical Co., Ltd.
- 当前专利权人地址： KRX Chungnam
- 优先权： KRX93-13227 19930714
- 主分类号： A61K31/12
- IPC分类号： A61K31/12 ; A61K31/122 ; A61K31/215 ; A61P35/00 ; C07C43/20 ; C07C43/23 ; C07C46/00 ; C07C46/02 ; C07C46/06 ; C07C50/32 ; C07C67/03 ; C07C67/28 ; C07C69/007 ; C07C69/18 ; C07C69/30 ; C07C69/533 ; C07C69/58 ; C07C69/587 ; C07C69/608 ; C07C69/614 ; C07C69/63 ; C07C69/65
摘要：
5,8-dihydroxynaphthoquinone derivatives represented by the following general formula (IA): ##STR1## in which R.sup.1 represents alkyl or alkenyl, R.sup.2a represents alkyl or a group --C(O)R wherein R represents alkyl, alkenyl, aryl, aralkyl or aralkenyl, which can be substituted or unsubstituted with one or more halogen(s), and R.sup.3 represents hydrogen or alkyl, provided that when R.sup.2a is a group --C(O)R and R.sup.3 is hydrogen, R.sup.1 is other than 3-methyl-2-butenyl; and when R.sup.2a represents methyl and R.sup.3 independently represents hydrogen or methyl, R.sup.1 is other than 3-methylbutyl. Processes for preparing 5,8-dihydroxynaphthoquinone derivatives are also provided.
公开/授权文献
- USD321260S Lamp 公开/授权日：1991-10-29
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