发明授权
US5698576A Use of imidazopyrazole derivatives as analgesics anti-inflammatory agents
失效
使用咪唑并吡唑衍生物作止痛剂抗炎剂
- 专利标题: Use of imidazopyrazole derivatives as analgesics anti-inflammatory agents
- 专利标题(中): 使用咪唑并吡唑衍生物作止痛剂抗炎剂
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申请号: US755290申请日: 1996-11-22
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公开(公告)号: US5698576A公开(公告)日: 1997-12-16
- 发明人: Atsusuke Terada , Kazuyuki Wachi , Hachio Miyazawa , Yoshio Iizuka , Kazuo Hasegawa , Keiichi Tabata
- 申请人: Atsusuke Terada , Kazuyuki Wachi , Hachio Miyazawa , Yoshio Iizuka , Kazuo Hasegawa , Keiichi Tabata
- 申请人地址: JPX Tokyo
- 专利权人: Sankyo Company, Limited
- 当前专利权人: Sankyo Company, Limited
- 当前专利权人地址: JPX Tokyo
- 优先权: JPX6-186132 19880726
- 主分类号: A61K31/415
- IPC分类号: A61K31/415 ; A61K31/4188 ; A61K31/422 ; A61K31/4439 ; A61K31/4725 ; C07D487/04 ; C07D235/00
摘要:
Described herein are compounds of formula (I): ##STR1## �in which: R.sup.1 and R.sup.2 are hydrogen, optionally substituted alkyl, cycloalkyl, alkenyl, aralkyl, arylalkenyl, aryl, aromatic heterocyclic, cyano or halogen; R.sup.3 is hydrogen, optionally substituted alkyl, aralkyl or acyl; R.sup.4 and R.sup.5 are hydrogen, optionally substituted alkyl, cycloalkyl, alkenyl, aralkyl, arylalkenyl, aryl or aromatic heterocyclic!; and pharmaceutically acceptable salts thereof are analgesics and anti-inflammatory agents as well having anti-ulcer and 5-lipoxygenase inhibitory activities.
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