发明授权
US5698711A Compounds containing phenyl linked to aryl or heteroaryl by an
aliphatic- or heteroatom-containing linking group
失效
含有通过含脂肪族或含杂原子的连接基与芳基或杂芳基连接的苯基的化合物
- 专利标题： Compounds containing phenyl linked to aryl or heteroaryl by an aliphatic- or heteroatom-containing linking group
- 专利标题（中）： 含有通过含脂肪族或含杂原子的连接基与芳基或杂芳基连接的苯基的化合物
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申请号： US487377申请日： 1995-06-07
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公开(公告)号： US5698711A公开(公告)日： 1997-12-16
- 发明人: Malcolm Norman Palfreyman
- 申请人： Malcolm Norman Palfreyman
- 申请人地址： GBX Kent
- 专利权人： Rhone-Poulenc Rorer Limited
- 当前专利权人： Rhone-Poulenc Rorer Limited
- 当前专利权人地址： GBX Kent
- 优先权： GBX9101777 19910128; GBX9117727 19910816; GBX9216005 19920728; GBX9216006 19920728; GBX9216008 19920728; GBX9310633 19930521; GBX9314847 19930716
- 主分类号： C07C43/225
- IPC分类号： C07C43/225 ; C07C45/00 ; C07C45/29 ; C07C45/71 ; C07C47/575 ; C07C49/84 ; C07C59/58 ; C07C59/60 ; C07C59/62 ; C07C65/21 ; C07C65/24 ; C07C65/26 ; C07C65/42 ; C07C69/76 ; C07C69/92 ; C07C205/59 ; C07C217/88 ; C07C235/56 ; C07C255/57 ; C07C255/60 ; C07C275/34 ; C07C311/29 ; C07C311/46 ; C07C317/40 ; C07C323/42 ; C07C327/48 ; C07D213/50 ; C07D213/75 ; C07D213/89 ; C07D239/42 ; C07D241/20 ; C07D261/14 ; C07D275/02 ; C07D275/03 ; C07D409/12 ; C07D333/02 ; C07C13/10 ; C07C3/20
摘要：
This invention is directed to the pharmaceutical use of phenyl compounds, which are linked to an aryl moiety by various linkages, for inhibiting tumor necrosis factor. The invention is also directed to the compounds, their preparation and pharmaceutical compositions containing these compounds. Furthermore, this invention is directed to the pharmaceutical use of the compounds for inhibiting cyclic AMP phosphodiesterase.
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