A large-sized liquid crystal panel uniformly filled with a liquid crystal material may be produced through a process including the steps of: fixing a pair of substrates with a sealing member disposed therebetween to form a blank panel having an injection port, reducing a pressure within the panel, applying a liquid crystal material onto the injection port, heating the liquid crystal material to its isotropic temperature, injecting the liquid crystal material into the panel under a pressure, and filling the panel with the liquid crystal material under heating and pressurization from the injection port toward the panel inside. The pressure within the panel before the injection is reduced at a rate not exceeding 25 torr/min. The pressure for injection is increased at varying rates, e.g., with an intermediate constant pressure period. In the filling step, a portion of the liquid crystal material near the injection port is held in its isotropic phase and the liquid crystal material except for the portion is transformed at least once into a smectic phase.