发明授权
US5700826A 1,2,4,5-tetra substituted imidazoles as modulators of multi-drug
resistance
失效
1,2,4,5-四取代的咪唑作为多药耐药的调节剂
- 专利标题： 1,2,4,5-tetra substituted imidazoles as modulators of multi-drug resistance
- 专利标题（中）： 1,2,4,5-四取代的咪唑作为多药耐药的调节剂
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申请号： US481118申请日： 1995-06-07
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公开(公告)号： US5700826A公开(公告)日： 1997-12-23
- 发明人: Adnan Mjalli , Sepehr Sarshar
- 申请人： Adnan Mjalli , Sepehr Sarshar
- 申请人地址： CA Carlsbad
- 专利权人： Ontogen Corporation
- 当前专利权人： Ontogen Corporation
- 当前专利权人地址： CA Carlsbad
- 主分类号： C07D233/54
- IPC分类号： C07D233/54 ; C07D233/56 ; C07D233/61 ; C07D409/04 ; C07D521/00 ; A61K31/415 ; C07D233/04
摘要：
This invention relates to compounds of Formula 1 which are pharmacologically useful for the treatment of cancer through sensitization of multi-drug resistant cancer cells to chemotherapeutic agents. ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, and R.sub.4 are, respectively hydrogen, alkyl, alkenyl, substituted alkyl, substituted alkenyl, aryl, substituted aryl.
公开/授权文献
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