发明授权
US5705657A Isocyanate process for the preparation of 1,3A,8-trimethyl-1,2,3,3A, 8,
8A-hexahydro-pyrrole �2,3-B! indol-5 (3AS, 8AR) -hepthylcarbamate
失效
用于制备1,3A,8-三甲基-1,2,3,3a,8,8a-六氢 - 吡咯并[2,3-B]吲哚-5(3AS,8AR) - 庚基氨基甲酸酯的异氰酸酯法
- 专利标题: Isocyanate process for the preparation of 1,3A,8-trimethyl-1,2,3,3A, 8, 8A-hexahydro-pyrrole �2,3-B! indol-5 (3AS, 8AR) -hepthylcarbamate
- 专利标题(中): 用于制备1,3A,8-三甲基-1,2,3,3a,8,8a-六氢 - 吡咯并[2,3-B]吲哚-5(3AS,8AR) - 庚基氨基甲酸酯的异氰酸酯法
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申请号: US416572申请日: 1995-04-04
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公开(公告)号: US5705657A公开(公告)日: 1998-01-06
- 发明人: Stefano Maiorana , Anna Bonura , Giorgio Chiodini
- 申请人: Stefano Maiorana , Anna Bonura , Giorgio Chiodini
- 申请人地址: ITX Milan
- 专利权人: Labochim Laboratorio Chimico Internazionale S.p.A.
- 当前专利权人: Labochim Laboratorio Chimico Internazionale S.p.A.
- 当前专利权人地址: ITX Milan
- 优先权: ITXMI91A0388 19910214
- 主分类号: C07D487/04
- IPC分类号: C07D487/04
摘要:
A process for the preparation of 1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro-pyrrole�2,3-b!indol-5(3aS,8aR)-heptylcarbamate, of formula (I) ##STR1## by reacting eseroline with heptylisocyanate in the presence of a metal cyanate and of a quaternary ammonium salt, in polar aprotic solvents.
公开/授权文献
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