发明授权
- 专利标题: Use of prosaposin and neurotrophic peptides derived therefrom
- 专利标题(中): 使用由其衍生的炔诺酮和神经营养肽
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申请号: US484594申请日: 1995-06-07
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公开(公告)号: US5714459A公开(公告)日: 1998-02-03
- 发明人: John S. O'Brien , Yasuo Kishimoto
- 申请人: John S. O'Brien , Yasuo Kishimoto
- 申请人地址: CA La Jolla
- 专利权人: Myelos Neurosciences Corp.
- 当前专利权人: Myelos Neurosciences Corp.
- 当前专利权人地址: CA La Jolla
- 主分类号: A61K38/00
- IPC分类号: A61K38/00 ; C07K14/47 ; C07K14/475 ; C07K14/52 ; C07K14/705 ; C07K14/71 ; C07K14/715 ; A61K38/10 ; A61K38/18
摘要:
Prosaposin, saposin C and various peptide fragments of saposin C stimulate neurite outgrowth in vitro. In addition, prosaposin and saposin C promote increased myelination ex vivo. Prosaposin is present in large neurons of the brain, including both upper and lower motor neurons.
公开/授权文献
- US4995665A Sunroof structure for motor vehicle 公开/授权日:1991-02-26
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