- 专利标题: Method of skin regeneration using a collagen-glycosaminoglycan matrix and cultured epithelial autograft
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申请号: US596060申请日: 1996-02-06
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公开(公告)号: US5716411A公开(公告)日: 1998-02-10
- 发明人: Dennis P. Orgill , Charles E. Butler , Mark Barlow , Scott Ritterbush , Ioannis V. Yannas , Carolyn C. Compton
- 申请人: Dennis P. Orgill , Charles E. Butler , Mark Barlow , Scott Ritterbush , Ioannis V. Yannas , Carolyn C. Compton
- 申请人地址: MA Boston MA Cambridge FL Tampa
- 专利权人: Brigham & Womens Hospital,Massachusetts Institute of Technology,Shriners Hospitals for Crippled Children
- 当前专利权人: Brigham & Womens Hospital,Massachusetts Institute of Technology,Shriners Hospitals for Crippled Children
- 当前专利权人地址: MA Boston MA Cambridge FL Tampa
- 主分类号: A61F2/00
- IPC分类号: A61F2/00 ; A61F2/10 ; A61L27/24 ; A61L27/60
摘要:
The present invention relates to a method of skin regeneration of a wound or burn in an animal or human. This method comprises the steps of initially covering the wound with a collagen glycosaminoglycan matrix, allowing infiltration of the grafted GC matrix by mesenchymal cells and blood vessels from healthy underlying tissue and applying a cultured epithelial autograft sheet grown from epidermal cells taken from the animal or human at a wound free site on the animal's or human's body surface. The resulting graft has excellent take rates and has the appearance, growth, maturation and differentiation of normal skin.
公开/授权文献
- US4609989A Method and machine for manufacturing artificial branches 公开/授权日:1986-09-02
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