发明授权
US5717063A Octacyclodepsipeptides having an endoparasiticidal action
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具有内寄生性杀伤作用的Octacyclodepsipeptide
- 专利标题: Octacyclodepsipeptides having an endoparasiticidal action
- 专利标题(中): 具有内寄生性杀伤作用的Octacyclodepsipeptide
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申请号: US456148申请日: 1995-05-31
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公开(公告)号: US5717063A公开(公告)日: 1998-02-10
- 发明人: Jurgen Scherkenbeck , Peter Jeschke , Hans-Georg Lerchen , Hermann Hagemann , Achim Harder , Norbert Mencke , Andrew Plant
- 申请人: Jurgen Scherkenbeck , Peter Jeschke , Hans-Georg Lerchen , Hermann Hagemann , Achim Harder , Norbert Mencke , Andrew Plant
- 申请人地址: DEX Leverkusen
- 专利权人: Bayer Aktiengesellschaft
- 当前专利权人: Bayer Aktiengesellschaft
- 当前专利权人地址: DEX Leverkusen
- 优先权: DEX4317432.9 19930526
- 主分类号: A01N43/72
- IPC分类号: A01N43/72 ; A61K31/395 ; A61K38/00 ; A61P33/00 ; A61P33/10 ; C07D273/00 ; C07K1/113 ; C07K11/02 ; A61K38/15 ; C07K11/00
摘要:
The present invention relates to compounds of the general formula (I) ##STR1## in which R.sup.1 and R.sup.12 represent the same or different radicals selected from the group of C.sub.2-9 -alkyl, C.sub.1-8 -halogeno-alkyl, C.sub.3-6 -cycloalkyl, aralkyl or aryl, R.sup.3 to R.sup.10 represent the same or different radicals selected from the group of hydrogen, C.sub.1-5 -alkyl which may optionally be substituted by hydroxyl, alkoxy, carboxyl, carboxamide, imidazolyl, indolyl, guanidino, thio- or thioalkyl, and represent aryl, alkylaryl or heteroarylmethyl which are optionally substituted by halogen, hydroxyl, alkyl, alkoxy, nitro or a --NR.sup.13 R.sup.14 group in which R.sup.13 or R.sup.14 independently from each other represent hydrogen or alkyl or together with the adjoining nitrogen atom form a 5, 6 or 7-membered ring which is optionally interrupted by O, S or N and which is optionally substituted by C.sub.1-4 -alkyl, R.sup.2 and R.sup.11 represent the same of different radicals selected from the group of C.sub.1-4 -alkyl, and stereoisomers thereof, to processes for their preparation and to their use as endoparasiticides.
公开/授权文献
- US5110324A Electrostatic separation method and apparatus 公开/授权日:1992-05-05
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