发明授权
US5718903A Vaccine comprising Brucella abortus which has O polysaccharide antigen
absent
失效
含有O多糖抗原的布鲁氏菌流产的疫苗不存在
- 专利标题: Vaccine comprising Brucella abortus which has O polysaccharide antigen absent
- 专利标题(中): 含有O多糖抗原的布鲁氏菌流产的疫苗不存在
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申请号: US196777申请日: 1994-02-14
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公开(公告)号: US5718903A公开(公告)日: 1998-02-17
- 发明人: Leslie Garry Adams , Richard P. Crawford , Donald S. Davis , Thomas A. Ficht , Roger Smith, III , Blair A. Sowa , Joe W. Templeton , John D. Williams , Albert M. Wu
- 申请人: Leslie Garry Adams , Richard P. Crawford , Donald S. Davis , Thomas A. Ficht , Roger Smith, III , Blair A. Sowa , Joe W. Templeton , John D. Williams , Albert M. Wu
- 申请人地址: TX College Station
- 专利权人: The Texas A&M University System
- 当前专利权人: The Texas A&M University System
- 当前专利权人地址: TX College Station
- 主分类号: A61K39/00
- IPC分类号: A61K39/00 ; C07K14/23 ; C12N1/21 ; A61K39/10
摘要:
The present invention is an improved vaccine against Brucella abortus which permits differentiation between vaccinated and field strain infected cattle. The vaccine can be administered in two different forms: (1) cell envelopes isolated from an O polysaccharide antigen deficient, stable transposon mutant of B. abortus or (2) an O polysaccharide antigen deficient, stable transposon mutant of B. abortus.
公开/授权文献
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