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    MICROFLUIDIC DEVICE MIMICKING TUMOR MICROENVIRONMENT
    3.
    发明公开
    MICROFLUIDIC DEVICE MIMICKING TUMOR MICROENVIRONMENT 审中-公开

    公开(公告)号：US20240327768A1

    公开(公告)日：2024-10-03

    申请号：US18574081

    申请日：2022-07-07

    申请人： The Texas A&M University System

    发明人： Abhishek Jain ,  James J. Tronolone ,  Biswajit Saha

    IPC分类号： C12M3/06 ,  C12M1/12 ,  C12M3/00

    CPC分类号： C12M23/16 ,  C12M21/08 ,  C12M25/14

    摘要： In an embodiment, the present disclosure pertains to a medical device. In some embodiments, the medical device includes a first compartmentalized microfluidic channel flanked by two microchannels and a second compartmentalized microfluidic channel. In some embodiments, the first and second compartmentalized microfluidic channels are situated vertically one to another. In some embodiments, the medical device further includes a porous membrane situated between the first and second compartmentalized microfluidic channels. In another embodiment, the present disclosure pertains to an organ-on-chip. In some embodiments, the organ-on-chip includes a top portion having three parallel microchannels. In some embodiments, the three parallel microchannels are separated by micropillars. In some embodiments, the organ-on-chip further includes a bottom portion having a fourth microchannel and a membrane between the top portion and the bottom portion.

    Efficient mechanical generation of cavitation in liquids
    4.
    发明授权
    Efficient mechanical generation of cavitation in liquids 有权

    公开(公告)号：US12104625B2

    公开(公告)日：2024-10-01

    申请号：US17517996

    申请日：2021-11-03

    申请人： The Texas A & M University System

    发明人： David Staack ,  Xin Tang

    IPC分类号： F15D1/00

    CPC分类号： F15D1/007

    摘要： In an embodiment, the present disclosure pertains to a cavitation generation device that includes a dactyl plunger rotatable about an axis between an open position and a closed position and a propus socket having a channel. The propus socket is rigidly mounted below the dactyl plunger, and the dactyl plunger is received into the propus socket when the dactyl plunger is in the closed position. The cavitation generation device can also include a torsion spring that biases the dactyl plunger into contact with the propus socket. In another embodiment, the present disclosure pertains to a method of inducing a cavitation including biasing a dactyl plunger via a torsion spring, and rotating the dactyl plunger, by action of the torsion spring, into a propus socket. The propus socket includes a nozzle-shaped channel. The method further includes ejecting a socket cavity volume through the nozzle-shaped channel thereby inducing a cavitation event.

    MOBILE SURGICAL UNIT
    6.
    发明公开
    MOBILE SURGICAL UNIT 审中-公开

    公开(公告)号：US20240261164A1

    公开(公告)日：2024-08-08

    申请号：US18435506

    申请日：2024-02-07

    申请人： THE TEXAS A&M UNIVERSITY SYSTEM

    发明人： Brayden RAPER ,  Neil Koby REID ,  Jacob PARIS ,  William HENDRICKS

    IPC分类号： A61G10/00

    CPC分类号： A61G10/005

    摘要： The present disclosure provides systems and methods for the benefit of surgical procedures in such austere locations. As described herein, the technology is applicable anywhere in the world where access to medical care is limited or not available but necessary, especially more than one hour away by transport. These applications include space, military field medicine, recreational wilderness medicine, sites of disasters (e.g., earthquakes, tsunamis, building collapses, etc.), healthcare in rural or underdeveloped locations, and hospitals or clinics with resource shortages or limitations.

    MULTISPECTRAL OPTICAL FINGER SYSTEM FOR PHYSIOLOGICAL MEASUREMENTS
    8.
    发明公开
    MULTISPECTRAL OPTICAL FINGER SYSTEM FOR PHYSIOLOGICAL MEASUREMENTS 审中-公开

    公开(公告)号：US20240249553A1

    公开(公告)日：2024-07-25

    申请号：US18418887

    申请日：2024-01-22

    申请人： THE TEXAS A&M UNIVERSITY SYSTEM

    发明人： Kimberly BRANAN ,  Gerard L. COTE ,  Justin MCMURRAY

    IPC分类号： G06V40/145 ,  G06F3/01

    CPC分类号： G06V40/145 ,  G06F3/014

    摘要： Wearable optical devices, methods and systems for obtain dynamic and static physiological parameters from a subject are disclosed. Example devices can be worn around an appendage, such as a finger, and utilize PPG sensors to obtain signals from the appendage. The PPG sensors are positioned to acquire signals suitable to reconstruct an image of the inner appendage using, for example, diffuse optical tomography, to provide additional information. The devices, methods, and systems can obtain dynamic and static physiological parameters and accurate images in real-time.