发明授权
- 专利标题: Therapeutic treatment for cardiovascular diseases
- 专利标题(中): 心血管疾病治疗
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申请号: US662623申请日: 1996-06-13
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公开(公告)号: US5723456A公开(公告)日: 1998-03-03
- 发明人: Michael R. Jirousek , William Francis Heath, Jr. , Douglas Kirk Ways , Lawrence E. Stramm
- 申请人: Michael R. Jirousek , William Francis Heath, Jr. , Douglas Kirk Ways , Lawrence E. Stramm
- 申请人地址: IN Indianapolis
- 专利权人: Eli Lilly & Company
- 当前专利权人: Eli Lilly & Company
- 当前专利权人地址: IN Indianapolis
- 主分类号: C07D487/22
- IPC分类号: C07D487/22 ; A61K31/00 ; A61K31/40 ; A61K31/407 ; A61P3/00 ; A61P3/06 ; A61P3/10 ; A61P9/00 ; A61P9/10 ; A61P9/12 ; A61P13/00 ; A61P43/00 ; C07C43/174 ; C07C43/178 ; C07D498/22 ; C07D513/22 ; C07F7/18 ; A61K31/55
摘要:
A method for treating endothelial cell dysfunction, such as associated with cardiovascular disease are disclosed, particularly using the isozyme selective PKC inhibitor, (S)-3,4-�N,N'-1,1'-((27"-ethoxy)-3'"(O)-4'"-(N,N-dimethylamino)-butane)-bis-(3,3'-indolyl)!-1(H)-pyrrole-2,5-dione hydrochloride salt.
公开/授权文献
- US5242008A Method and apparatus for producing cores for foundry purposes 公开/授权日:1993-09-07
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