发明授权
US5728543A Clostripain catalyzed hydrolysis of preproinsulin analogs into
corresponding insulins
失效
梭菌素催化前胰岛素类似物水解成相应的胰岛素
- 专利标题: Clostripain catalyzed hydrolysis of preproinsulin analogs into corresponding insulins
- 专利标题(中): 梭菌素催化前胰岛素类似物水解成相应的胰岛素
-
申请号: US291060申请日: 1994-08-08
-
公开(公告)号: US5728543A公开(公告)日: 1998-03-17
- 发明人: Michael Dorschug , Klaus-Peter Koller , Rudiger Marquardt , Johannes Meiwes
- 申请人: Michael Dorschug , Klaus-Peter Koller , Rudiger Marquardt , Johannes Meiwes
- 申请人地址: DEX Frankfurt am Main
- 专利权人: Hoechst Aktiengesellschaft
- 当前专利权人: Hoechst Aktiengesellschaft
- 当前专利权人地址: DEX Frankfurt am Main
- 优先权: DEX4028118.3 19900905
- 主分类号: C12N9/52
- IPC分类号: C12N9/52 ; C07K14/62 ; C12N9/48 ; C12N15/09 ; C12P21/02 ; C12P21/06 ; A61K38/28
摘要:
A process is described to specifically hydrolyze the amino acid chain of preproinsulin analogs to give the corresponding insulins. The hydrolysis is catalyzed by clostripain and, if necessary, carboxypeptidase B.
公开/授权文献
- US06162635A Enzyme-producing strain of Bacillus bacteria 公开/授权日:2000-12-19
信息查询
IPC分类: