- 专利标题: Stilbene derivatives and pharmaceutical compositions containing them
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申请号: US613005申请日: 1996-03-08
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公开(公告)号: US5731353A公开(公告)日: 1998-03-24
- 发明人: Koji Ohsumi , Takashi Tsuji , Yoshihiro Morinaga , Kazuo Ohishi
- 申请人: Koji Ohsumi , Takashi Tsuji , Yoshihiro Morinaga , Kazuo Ohishi
- 申请人地址: JPX Tokyo
- 专利权人: Ajinomoto Co., Inc.
- 当前专利权人: Ajinomoto Co., Inc.
- 当前专利权人地址: JPX Tokyo
- 优先权: JPX5-223573 19930908
- 主分类号: C07C205/35
- IPC分类号: C07C205/35 ; C07C205/37 ; C07C217/80 ; C07C217/84 ; C07C255/43 ; A61K31/135
摘要:
A stilbene derivative of the following general formula (I) or a pharmaceutically acceptable acid addition salt thereof have low toxicity, but are water soluble and effective as carcinostatics: ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3, which may be the same or different, each represent an alkyl group having 1 to 3 carbon atoms; X represents a hydrogen atom or a nitrile group; Y represents an alkyloxy group having 1 to 3 carbon atoms, an alkyl group having 1 to 6 carbon atoms or a halogen atom.