发明授权
- 专利标题: 8-substituted xanthine derivatives and method of use thereof
- 专利标题(中): 8-取代黄嘌呤衍生物及其使用方法
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申请号: US477157申请日: 1995-06-07
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公开(公告)号: US5734051A公开(公告)日: 1998-03-31
- 发明人: Barbara Ann Spicer , Harry Smith , Harald Maschler
- 申请人: Barbara Ann Spicer , Harry Smith , Harald Maschler
- 申请人地址: GBX Brentford
- 专利权人: Beecham Group
- 当前专利权人: Beecham Group
- 当前专利权人地址: GBX Brentford
- 优先权: GBX8906792 19890323
- 主分类号: C07D473/04
- IPC分类号: C07D473/04 ; A61K31/52 ; A61K31/522 ; A61K31/535 ; A61K31/5377 ; A61P9/00 ; A61P9/08 ; A61P9/10 ; A61P11/00 ; A61P25/00 ; A61P25/28 ; A61P37/08 ; C07D239/545 ; C07D473/06 ; C07D473/08
摘要:
A method for the treatment of cerebrovascular disorders and/or disorders associated with cerebral senility and/or other disorders which method comprises the administration of an effective, non-toxic amount of a compound of formula (I): ##STR1## or if appropriate a pharmaceutically acceptable salt thereof, wherein R.sup.1 and R.sup.2 each independently represent alkyl or a moiety of formula (a): --(CH.sub.2).sub.m --A (a) wherein m represents zero or an integer 1, 2 or 3; A represents a substituted or unsubstituted cyclic hydrocarbon radical; andR.sup.3 represents a halogen atom, a nitro group, or a group --NR.sup.4 R.sup.5 wherein R.sup.4 and R.sup.5 each independently represents hydrogen, alkyl or alkylcarbonyl or R.sup.4 and R.sup.5 together with the nitrogen to which they are attached forming an optionally substituted, heterocyclic group; certain novel compounds falling within formula (I) and compositions comprising such compounds.
公开/授权文献
- US4975197A Orbal wastewater treatment process 公开/授权日:1990-12-04
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