Invention Grant
- Patent Title: Human tissue plasminogen activator
- Patent Title (中): 人体组织纤溶酶原激活物
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Application No.: US472549Application Date: 1995-06-06
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Publication No.: US5753486APublication Date: 1998-05-19
- Inventor: David V. Goeddel , William J. Kohr , Diane Pennica , Gordon A. Vehar
- Applicant: David V. Goeddel , William J. Kohr , Diane Pennica , Gordon A. Vehar
- Applicant Address: CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: CA South San Francisco
- Main IPC: A61K38/00
- IPC: A61K38/00 ; C12N1/21 ; C12N9/06 ; C12N9/72 ; C12N15/58 ; C12N15/71 ; C12P20060101 ; C12N9/50 ; A61K38/49 ; C12N9/64 ; C12N15/55
Abstract:
A human tissue plasminogen activator (t-PA) is produced in useful quantities using recombinant DNA techniques. The invention disclosed thus enables the production of t-PA free of contaminants with which it is ordinarily associated in its native cellular environment. Methods, expression vehicles and various host cells useful in its production are also disclosed.
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