发明授权
- 专利标题： Adenoviruses having modified fiber proteins
- 专利标题（中）： 具有修饰的纤维蛋白的腺病毒
-
申请号： US591492申请日： 1996-02-06
-
公开(公告)号： US5756086A公开(公告)日： 1998-05-26
- 发明人: Alan McClelland , Susan C. Stevenson
- 申请人： Alan McClelland , Susan C. Stevenson
- 申请人地址： MD Gaithersburg
- 专利权人： Genetic Therapy, Inc.
- 当前专利权人： Genetic Therapy, Inc.
- 当前专利权人地址： MD Gaithersburg
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; A61K48/00 ; C07K14/075 ; C07K14/475 ; C07K14/525 ; C07K14/775 ; C12N7/04 ; C12N9/64 ; C12N15/34 ; C12N15/861 ; C12N15/87 ; C12N15/86 ; C12N15/62
摘要：
An adenovirus wherein the adenovirus fiber protein includes a ligand which is specific for a receptor located on a desired cell type. The adenovirus may have at least a portion of the adenovirus fiber protein removed and replaced with a ligand which is specific for a receptor located on a desired cell type, or the adenovirus may include a fusion protein of the adenovirus fiber protein and the ligand. Such an adenovirus may also include a gene(s) encoding a therapeutic agent(s) and may be "targeted" in order to deliver such gene(s) to a desired cell type.
公开/授权文献
- USD329965S Potato cutter 公开/授权日：1992-10-06
信息查询
IPC分类:
