发明授权
- 专利标题: Tissue plasminogen activator variants
- 专利标题(中): 组织纤溶酶原激活物变体
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申请号: US275335申请日: 1994-07-14
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公开(公告)号: US5756093A公开(公告)日: 1998-05-26
- 发明人: Herbert L. Heyneker , Gordon A. Vehar , Nicholas F. Paoni , William F. Bennett
- 申请人: Herbert L. Heyneker , Gordon A. Vehar , Nicholas F. Paoni , William F. Bennett
- 申请人地址: CA So. San Francisco
- 专利权人: Genentech, Inc.
- 当前专利权人: Genentech, Inc.
- 当前专利权人地址: CA So. San Francisco
- 主分类号: A61K38/00
- IPC分类号: A61K38/00 ; C12N1/21 ; C12N9/72 ; A61K38/48 ; C07H21/04 ; C12N9/48
摘要:
Biologically active variant tissue plasminogen activators are disclosed. The disclosure focuses on position 276 variants that exhibit enhanced fibrin specificity.
公开/授权文献
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