发明授权
- 专利标题： Recombinant poxviruses with foreign DNA in essential regions
- 专利标题（中）： 重要痘病毒与外来DNA在必需区域
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申请号： US802985申请日： 1997-02-21
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公开(公告)号： US5770212A公开(公告)日： 1998-06-23
- 发明人: Falko-Gunter Falkner , Georg Holzer , Friedrich Dorner
- 申请人： Falko-Gunter Falkner , Georg Holzer , Friedrich Dorner
- 申请人地址： ATX Vienna
- 专利权人： Immuno Aktiengesellschaft
- 当前专利权人： Immuno Aktiengesellschaft
- 当前专利权人地址： ATX Vienna
- 主分类号： A01K67/027
- IPC分类号： A01K67/027 ; A61K39/00 ; C07K14/07 ; C07K14/16 ; C12N5/10 ; C12N7/00 ; C12N7/01 ; C12N15/09 ; C12N15/39 ; C12N15/863 ; C12R1/92 ; A61K39/285 ; A61K39/002 ; A61K39/02 ; A61K39/12 ; A61K39/275
摘要：
Defective poxviruses that lack a function imparted by an essential region of its parental poxvirus are provided for protein production and vaccination. A DNA polynucleotide encoding a protein is inserted into the defective poxvirus and placed under transcriptional control of a promoter. The defective poxvirus is viable when the lost function of the essential region is complemented by a host cell, transgenic animal or helper virus.
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