发明授权
US5773010A Low molecular weight allergen obtained from Dermatophagoides farinae
失效
从Dermatophagoides farinae获得的低分子量过敏原
- 专利标题: Low molecular weight allergen obtained from Dermatophagoides farinae
- 专利标题(中): 从Dermatophagoides farinae获得的低分子量过敏原
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申请号: US564395申请日: 1995-11-29
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公开(公告)号: US5773010A公开(公告)日: 1998-06-30
- 发明人: Satoru Oka , Kazuhisa Ono , Seiko Shigeta , Takeshi Wada
- 申请人: Satoru Oka , Kazuhisa Ono , Seiko Shigeta , Takeshi Wada
- 申请人地址: JPX Tokyo JPX Hiroshima-ken
- 专利权人: Fumakilla Limited,Hiroshima University
- 当前专利权人: Fumakilla Limited,Hiroshima University
- 当前专利权人地址: JPX Tokyo JPX Hiroshima-ken
- 优先权: JPX1-220064 19890824
- 主分类号: A61K39/35
- IPC分类号: A61K39/35 ; A61K38/00 ; A61K49/00 ; A61P37/08 ; C07K1/14 ; C07K14/00 ; C07K14/435 ; G01N33/53 ; A61B8/00 ; C12Q1/00
摘要:
New purified mite allergens useful as pharmaceutical and diagnostic compositions for the treatment and diagnosis of mite allergic diseases are provided. Both allergens are contained in fecal extracts of mites in culture. The high molecular weight allergen has a weight average molecular weight of 70,000 to 80,000 as determined by sedimentation equilibrium. This is a glycoprotein containing more than about 70% sugar, and possesses allergen activity. The low molecular weight antigen has a molecular weight of 1,500 to 5,000 as determined by Sephadex G25 gel filtration. This is a glycoprotein containing more than about 40% sugar, and also possesses allergen activity.
公开/授权文献
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