- 专利标题: Methods and compositions for inhibiting cell proliferative disorders
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申请号: US486775申请日: 1995-06-07
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公开(公告)号: US5773476A公开(公告)日: 1998-06-30
- 发明人: Hui Chen , Aviv Gazit , Alexander Levitzki , Klaus Peter Hirth , Elaina Mann , Laura K. Shawver , Jianming Tsai , Peng Cho Tang
- 申请人: Hui Chen , Aviv Gazit , Alexander Levitzki , Klaus Peter Hirth , Elaina Mann , Laura K. Shawver , Jianming Tsai , Peng Cho Tang
- 申请人地址: ILX Redwood City ILX Jerusalem
- 专利权人: Sugen, Inc.,Yissum Research and Development Company of the Hebrew University of Jerusalem
- 当前专利权人: Sugen, Inc.,Yissum Research and Development Company of the Hebrew University of Jerusalem
- 当前专利权人地址: ILX Redwood City ILX Jerusalem
- 主分类号: A61K31/245
- IPC分类号: A61K31/245 ; A61K31/277 ; A61K31/415 ; A61K31/4184 ; A61K31/4402 ; A61K31/498 ; A61K31/517 ; C07C229/60 ; C07C255/36 ; C07C255/37 ; C07C255/41 ; C07C255/42 ; C07C255/66 ; C07C311/27 ; C07C317/46 ; C07C327/44 ; C07D241/52 ; A01N37/18
摘要:
The present invention concerns compounds and their use to inhibit the activity of a receptor tyrosine kinase. The invention is preferably used to treat cell proliferative disorders such as cancers charcterized by over-activity or inappropriate activity HER2 or EGFR.
公开/授权文献
- US4531678A Injection valve 公开/授权日:1985-07-30
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