发明授权
US5780670A DTPA derivatives modified with non-ester bond and a process for
synthesizing them
失效
用非酯键修饰的DTPA衍生物及其合成方法
- 专利标题： DTPA derivatives modified with non-ester bond and a process for synthesizing them
- 专利标题（中）： 用非酯键修饰的DTPA衍生物及其合成方法
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申请号： US680611申请日： 1996-07-16
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公开(公告)号： US5780670A公开(公告)日： 1998-07-14
- 发明人: Yoshinori Yamamoto , Hisao Nemoto
- 申请人： Yoshinori Yamamoto , Hisao Nemoto
- 申请人地址： JPX Sendai
- 专利权人： Tohoku University
- 当前专利权人： Tohoku University
- 当前专利权人地址： JPX Sendai
- 优先权： JPX7-185306 19950721
- 主分类号： A61K49/00
- IPC分类号： A61K49/00 ; A61K51/04 ; B01J23/44 ; B01J31/22 ; C07B61/00 ; C07C227/18 ; C07C229/16 ; C07C229/24 ; C07C229/30 ; C07C229/00
摘要：
Provided are DTPA derivatives having five carbonyl groups, represented by the following formula (1). Further provided is a process for synthesizing a compound (1a) represented by the formula of a compound (1) in which R.sub.2 is 2-alkenyl group (R.sub.4). The process comprises the steps of performing esterification of DTPA, introducing an alkoxycarbonyl group and reacting with 2-alkenyl alkoxyformate in the presence of a palladium catalyst, thereby obtaining the compound (1a). ##STR1##
公开/授权文献
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