发明授权
- 专利标题: Therapeutic and diagnostic methods and compositions based on notch proteins and nucleic acids
- 专利标题(中): 基于缺口蛋白和核酸的治疗和诊断方法和组合物
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申请号: US83590申请日: 1993-06-25
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公开(公告)号: US5786158A公开(公告)日: 1998-07-28
- 发明人: Spyridon Artavanis-Tsakonas , Richard Grant Fehon , Panayiotis Zagouras , Christine Marie Blaumueller
- 申请人: Spyridon Artavanis-Tsakonas , Richard Grant Fehon , Panayiotis Zagouras , Christine Marie Blaumueller
- 申请人地址: CT New Haven
- 专利权人: Yale University
- 当前专利权人: Yale University
- 当前专利权人地址: CT New Haven
- 主分类号: G01N33/53
- IPC分类号: G01N33/53 ; A01N37/18 ; A61K31/70 ; A61K38/00 ; A61K38/17 ; A61K39/395 ; A61K48/00 ; A61P1/16 ; A61P17/00 ; A61P25/00 ; A61P35/00 ; A61P43/00 ; C07H21/04 ; C07K14/435 ; C07K14/47 ; C07K14/705 ; C12N1/21 ; C12N15/09 ; C12N15/62 ; C12P21/02 ; C12R1/19 ; G01N33/574 ; G01N33/68
摘要:
The present invention relates to diagnostic methods and compositions for detection of malignancy or nervous system disorders based on the level of Notch proteins or nucleic acids. Therapeutic methods and methods of inhibiting Notch expression are also provided.
公开/授权文献
- USD405369S Display box 公开/授权日:1999-02-09
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